Team Grant : Monkeypox Rapid Research Response

To be eligible to the competition, applications must be co-led by Canadian and African researchers and address all objectives:

• Provide rapid evidence to inform clinical and health system management and public health response, and/or decision-making and planning within and across jurisdictions in Canada and internationally;
• Undertake robust, multi-country cross learning, and comparative research (including in collaboration with other international researchers where appropriate) on:
  • the safety and real-world effectiveness of medical or other countermeasures deployed* (including vaccines and therapeutics) to treat and/or prevent monkeypox infections in people in Canada and globally; and
  • the underlying serological histories and transmission dynamics of the current monkeypox outbreaks in Canada and globally (including time of exposure and transmission during asymptomatic phase, mechanisms of human-to-human transmission, and key risk factors for infection and transmission);
• Align with and contribute to the WHO Global Clinical Platform for monkeypox and other international monkeypox surveillance and research coordination activities by:
  • adopting WHO case investigation and reporting forms;
  • developing robust study protocols that can be integrated and harmonized with international clinical datasets; and
  • contributing to global real-time sharing and analyses of research findings across different study contexts

*Please note that medical countermeasures against monkeypox (including vaccines, drugs and other therapeutic agents) will not be provided by the Government of Canada for research supported through this funding opportunity.