DOD Chronic Pain Management Research Program Funding Opportunities
The FY22 Defense Appropriations Act is anticipated to provide funding for the Chronic Pain Management Research Program (CPMRP) to support and promote innovative, high-impact research to prevent the development and improve the management of chronic pain, with specific emphasis on the utilization and implementation of non-opioid therapies or non-addictive complementary methods. Per the FY19 CPMRP congressional appropriation, chronic pain is defined as a pain that occurs on at least half the days for 6 months or more, and which can be caused by issues including, but not limited to: combat- and training-related physical or mental stress and trauma, migraines and chronic headaches, traumatic brain injury, arthritis, muscular-skeletal conditions, neurological disease, tick and vector-borne disease, other insect-transmitted or tropical disease, and cancer. The managing agent for the anticipated program announcements/funding opportunities is the CDMRP at the U.S. Army Medical Research and Development Command (USAMRDC).
The FY22 CPMRP funding opportunity announcements for the following award mechanisms is posted on the Grants.gov website.
Applications submitted to the FY22 CPMRP must address one or more of the following focus areas:
- Clinical Exploration Award
o Chronification of pain
o Effectiveness or observational studies of novel treatments or untested techniques/approaches/pathways to chronic pain management
- Investigator-Initiated Research Award
o Chronification of pain
o Development of non-opioid therapies and methods for the treatment of chronic pain
o Effectiveness or observational studies of novel treatments or untested techniques/approaches/pathways to chronic pain management
- Translational Research Award
o Comparative effectiveness studies (for evidence-based, efficacious interventions to manage or prevent chronic pain)
o Implementation science (for evidence-based, efficacious interventions to manage or prevent chronic pain)
o Observational studies related to chronic pain
Clinical Exploration Award – Preproposal due July 12, 2022
Independent investigators at all levels
- · Supports proof-of-principle pilot studies, clinical trials, and correlative studies with the potential to resolve current clinical barriers.
- · Research must address one or both of the FY22 CPMRP CEA Focus Areas of chronification of pain and effectiveness or observational studies of novel or untested techniques/approaches/pathways to chronic pain management.
- · Explorative studies, innovative approaches, and stakeholder engagement are encouraged.
- · Preliminary data are not required.
- · Statistically underpowered studies of efficacy are not pilot studies and will not be supported under the FY22 CPMRP CEA mechanism.
- · Pre-application submission is required; application submission is by invitation only.
- · The maximum allowable funding for the entire period of performance is $250,000 for direct costs.
- · Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
- · The maximum period of performance is 2 years.
Investigator-Initiated Research Award – Preproposal due July 12, 2022
Investigators at or above the level of Assistant Professor (or equivalent)
- · Supports innovative research that will make an original and important contribution to the field of research, patient care, and/or quality of life.
- · Research must address one of more of the FY22 CPMRP IIRA Focus Areas of chronification of pain, effectiveness or observational studies of novel or untested techniques/approaches/pathways to chronic pain management, or development of non-opioid therapies and methods of treatment of chronic pain.
- · Partnering Principal Investigator (PI) Option is available.
- · Multidisciplinary collaborations, innovative approaches, and stakeholder engagement are encouraged.
- · Clinical trials will not be funded.
- · Pre-application submission is required; application submission is by invitation only.
- · The maximum allowable funding for the entire period of performance is $900,000 for direct costs.
- · Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
- · The maximum period of performance is 4 years.
Translational Research Award – Preproposal due July 12, 2022
Investigators at or above the level of Assistant Professor (or equivalent)
- · Supports translational research that will accelerate the movement of efficacious, evidence-based ideas into clinical applications.
- · Research must address one or more of the FY22 CPMRP TRA Focus Areas of implementation science, comparative effectiveness, or observational studies related to chronic pain.
- · Incorporation of stakeholder engagement is required.
- · Biopsychosocial models of assessment are encouraged.
- · Partnering PI Option is available.
- · Studies seeking to evaluate new therapies or approaches, either pharmacological or non-pharmacological, that have not been previously evaluated in a clinical setting will not be funded.
- · Pre-application submission is required; application submission is by invitation only
- · The maximum allowable funding for the entire period of performance is $1,400,000 for direct costs.
- · Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
- · The maximum period of performance is 4 years.
A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final funding opportunity announcements that are available for downloading from the Grants.gov website. The application package containing the required forms for each award mechanism will also be found on Grants.gov. A listing of all CDMRP and other USAMRDC extramural funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.
For email notification when announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org. For more information about the CPMRP or other CDMRP-administered programs, please visit the CDMRP website (https://cdmrp.army.mil).
Point of Contact:
CDMRP Help Desk
301-682-5507
help@eBRap.org
For more information, please contact Jill Sherman, International Research Faciliator, at intl.research@lakeheadu.ca.