DoD Spinal Cord Injury Research Program Funding Opportunities
The FY22 Defense Appropriations Act is anticipated to provide funding for the SCIRP to support innovative, high-impact spinal cord injury (SCI) research.1 The managing agent for the anticipated program announcements/funding opportunities is the CDMRP at the U.S. Army Medical Research and Development Command (USAMRDC).
The FY22 SCIRP funding opportunity announcements for the following award mechanisms are posted on the Grants.gov website.
Applications submitted to the FY22 SCIRP must address one or more of the following Focus Areas†:
- · Preserving and protecting spinal cord tissue at time of injury for improved neurologic outcomes
- · Identifying and validating biomarkers for diagnosis, prognosis, and for evaluation of treatment efficacies
- · Developing, testing, and validating promising interventions to address bowel, genitourinary, neuropathic pain, cardiopulmonary, or autonomic dysfunction in people with SCI
- · Investigating psychosocial issues relevant to people with SCI, their families, and/or their care-partners
- · Rehabilitation and regeneration—maximizing the function of the residual neural circuitry, including harnessing neuroplasticity and recovery to improve function after SCI
Clinical Trial Award – Preproposal due May 23, 2022
Principal Investigator (PI): Investigators at all academic levels (or equivalent)
Optional Early-Career Partnering PI:
An independent, early-career investigator within 10 years after completion of terminal degree
- · Preproposal is required; application submission is by invitation only.
Funds the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of spinal cord injury (SCI). • Proposed projects may range from small proof-of-concept trials to demonstrate feasibility or inform the design of more advanced trials, through large-scale trials to determine efficacy in relevant populations. • Alternative trial designs to traditional randomized clinical trials are allowed but should be appropriate to the objective of the trial. • Community Collaborations in Research: Applications are expected to name at least two community partners (e.g., SCI Lived Experience Consultant, representative of community-based organization) who will provide advice and consultation throughout the planning and implementation of the research project. • Preliminary data required for all clinical trial applications. • Early-Career Partnering PI Option
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Translational Research Award – Preproposal due May 23, 2022
PI: Investigators at all academic levels (or equivalent)
Optional Early-Career Partnering PI:
An independent, early-career investigator within 10 years after completion of terminal degree
- · Preproposal is required; application submission is by invitation only.
- · Funds studies that accelerate the movement of promising ideas in SCI research into clinical applications.
• Community Collaborations in Research: Applications are expected to name at least one community partner (e.g., SCI Lived Experience Consultant, representative of community-based organization) who will provide advice and consultation throughout the planning and implementation of the research project.
• Preliminary data required.
• The SCIRP Translational Research Award may include a pilot clinical trial ONLY as a part of the proposed research where limited clinical testing of a novel intervention or device is necessary to inform the next step in the continuum of translational research.
• Early-Career Partnering PI Option
The maximum allowable funding for the entire period of performance is $1.25M for direct costs.
• Early-Career Partnering PI Option: Maximum allowable funding for the entire period of performance is $1.35M for direct costs.
• Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
• The maximum period of performance is 3 years.
Investigator-Initiated Research Award – Preproposal due May 23, 2021
PI: Investigators at all academic levels (or equivalent)
Optional Early-Career Partnering PI:
An independent, early-career investigator within 10 years after completion of his/her terminal degree
- · Preproposal is required; application submission is by invitation only.
Funds research that has the potential to make an important contribution to SCI research, patient care, and/or quality of life.
• Studies focused exclusively on target identification are discouraged.
• Preliminary data required.
• Clinical trials are not allowed.
• Early-Career Partnering PI Option
The maximum allowable funding for the entire period of performance is $0.50M for direct costs.
• Early-Career Partnering PI Option: Maximum allowable funding for the entire period of performance is $0.60M for direct costs.
• Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
• The maximum period of performance is 3 years.
A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final funding opportunity announcements available for downloading from the Grants.gov website. The application package containing the required forms for each award mechanism will also be found on Grants.gov. A listing of all CDMRP and other USAMRDC extramural funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.
For email notification when announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org. For more information about the SCIRP or other CDMRP-administered programs, please visit the CDMRP website (https://cdmrp.army.mil).
Point of Contact:
CDMRP Help Desk
301-682-5507
help@eBrap.org
1 Funding is provided through the FY22 appropriation for Peer-reviewed Spinal Cord Research
For more information, please contact Jill Sherman, International Research Facilitator, at intl.research@lakeheadu.ca .