Department of Physics Thesis Defense presented by Avner Fitterman
DEPARTMENT OF PHYSICS
Thesis Defense Presented By:
"Theory and Production of Hyperpolarized Xenon Gas for Lung and Brain
Magnetic Resonance Imaging"
Thursday, August 27th, 2015
In CB 4104
Conventional magnetic resonance imaging (MRI) modality is based on the magnetization that is formed by the influence of a strong polarizing magnetic field on the spin of protons, typically those of water molecules within the body. In Hyperpolarized (HP) gas MRI, a dramatic increase in spin polarization is achieved using spin-exchange optical pumping (SEOP), which allows images to be obtained with a high signal-to-noise ratio (SNR). Batch-mode custom-built polarizers can serve to produce the HP gas, however, such custom-built systems require optimization in terms of pressure and temperature parameters. This study is comprised of three objectives: i) Gaining understanding regarding the physics of the nuclear polarization process of 129Xe; ii) Examining experimentally the pressure and temperature dependences of the polarization, similarly to the way it was done in previous studies; iii) Exploiting this knowledge for the benefit of the optimization of the custom-built polarizer in our lab.