PhD Defense - Biotechnology: Ruth Amanna

Event Date: 
Thursday, September 4, 2025 - 1:30pm to 2:30pm EDT
Event Location: 
CB 4058
Event Contact Name: 
Brenda Magajna
Event Contact E-mail: 
phd.ses@lakeheadu.ca

Ruth Amanna will present her Biotechnology PhD research on Thursday, September 4 at 1:30 pm in CB 4058.

Title: Induction of actinobacterial enzymes for enhanced biodegradation of polyethylene terephthalate plastics

Short summary: The study addresses the environmental challenge of polyethylene terephthalate (PET) pollution using a biodegradation-based depolymerization strategy. It includes physicochemical modifications to enhance PET degradability, optimized cutinase enzyme production by Thermobifida fusca YX, and in silico investigations to identify potential PET-hydrolyzing enzymes. Techniques like UV photooxidation and reduced particle size improved biodegradation efficiency, with higher temperatures favoring whole-cell degradation. The optimization of cutinase production yielded a 42% increase, showcasing its potential for large-scale application. Lastly, six candidate cutinase enzymes were identified for their efficacy in PET degradation, emphasizing sustainable waste management solutions.

Committee Members: Dr. Sudip Kumar Rakshit (supervisor), Dr. Baoqiang Liao, Dr. Kang Kang and Dr. Animesh Dutta (external)

Everyone is welcome

For more information contact Brenda Magajna at phd.ses@lakeheadu.ca


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