DoD Peer Reviewed Alzheimer's Disease Research Funding Opportunities
The FY22 Defense Appropriations Act is anticipated to provide funding for the Peer Reviewed Alzheimer’s Disease Research Program (PRARP) to support research that addresses the long-term implications of military service as they pertain to Alzheimer’s disease (AD) and related dementias (ADRD) for Service Members, Veterans, and the general public. The managing agent for the anticipated program announcements/ funding opportunities is the CDMRP at the U.S. Army Medical Research and Development Command (USAMRDC).
The FY22 PRARP funding opportunity announcements for the following award mechanisms will be posted on the Grants.gov website
Applications submitted to the FY22 PRARP must address one or more of the following Focus Areas:
- Individual, caregiver, and family support: Research and resources focused on long-term care, quality of life, psychosocial wellness and support, and community and home resources supporting aging-in-place and community living for individuals living with dementia, their families, and care partners. Family is broadly defined to include family of choice as well. Study population diversity is strongly encouraged. Community-based participatory research inclusion is strongly preferred.
- Environmental, Diagnostic, and Prognostic Factors: Research to better detect, diagnose, and predict long-term outcomes and risk factors associated with AD/ADRD following military service and/or traumatic brain injury (TBI). Research of interest may include, but is not limited to:
○ Identification and validation of biomarkers for diagnosis and prognosis of AD and ADRD: including but not limited to fluid, tissues, imaging, device, and psychosocial, or a combination thereof.
○ Risk and resiliency factors for development of AD/ADRD during and after military service, such as genetic, physiological, psychosocial, and life history.
○ Epidemiological studies examining TBI and/or military service-related factors, including TBI and AD/ADRD development.
- Fundamental research to better understand the etiology, risk, and comorbidities for AD/ADRD after TBI.
, NEW: Investigator-Initiated Research Award – Letter of Intent due June 17, 2022
Single Principal Investigator (PI) Option
Independent investigators at all academic levels (or equivalent).
Early-Career Investigator Partnering PI Option
The Early-Career Investigator PI must be an independent investigator within 10 years of their terminal degree by the time of the application submission deadline (excluding time spent in residence or on family medical leave) or new to the field
Supports studies that will make important contributions to TBI and/or military-service-related factors as they pertain to AD/ADRD research, patient care, and quality of life.
Clinical trials are NOT allowed.
Community collaboration is required for projects involving clinical research.
Applications must address at least one of the following FY22 PRARP Focus Areas:
– Individual, caregiver, and family support (animal studies are NOT allowed for this Focus Area)
– Diagnostic, environmental, and prognostic factors
– Foundational research
The maximum allowable funding for the entire period of performance is $750,000 for total costs.
Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
The maximum period of performance is 3 years.
NEW: Translational Research Award – Letter of Intent due June 17, 2022
Independent investigators at or above the level of Assistant Professor (or equivalent).
Supports translational research that will accelerate the movement of promising products and knowledge in AD/ADRD research into clinical applications, including healthcare products and interventions, technologies, behavioral modalities, and/or clinical practice guidelines.
Supports both preclinical-to-clinical and clinical research-to-clinical care translation.
Clinical trials are NOT allowed.
Preliminary data are required.
Community collaboration is required for projects involving clinical research.
Applications must address at least one of the following FY22 PRARP Focus Areas:
– Individual, caregiver, and family support (animal studies are NOT allowed for this Focus Area)
– Diagnostic, environmental, and prognostic factors
– Foundational research
- The maximum allowable funding for the entire period of performance is $750,000 for total costs.
- Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
- The maximum period of performance Is 3 years.
Accelerating Diagnostics Research Award – Letter of Intent due June 17, 2022
Independent investigators at or above the level of Assistant Professor (or equivalent).
Supports high-impact advancement of robust diagnostic and/or prognostic factors pertaining to Alzheimer’s disease/Alzheimer’s disease-related dementias (AD/ADRD) following military service and/or traumatic brain injury (TBI).
Studies are required to prospectively recruit study participants.
Community collaboration is required.
Preliminary data are required.
Animal research is prohibited.
Clinical trials are NOT allowed.
Applications must address the following FY22 PRARP Focus Area:
– Diagnostic, environmental, and prognostic factors
The maximum allowable funding for the entire period of performance is $2,500,000 for total costs.
Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
The maximum period of performance is 4 years
A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final funding opportunity announcements available for downloading from the Grants.gov website. The application package containing the required forms for each award mechanism will also be found on Grants.gov. A listing of all CDMRP and other USAMRDC extramural funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.
For email notification when announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org. For more information about the PRARP or other CDMRP-administered programs, please visit the CDMRP website (https://cdmrp.army.mil).
Point of Contact:
CDMRP Help Desk
301-682-5507
help@eBrap.org
For more information, please contact Jill Sherman, International Research Facilitator at intl.research@lakeheadu.ca.