Operating Grant : Canadian Pediatric COVID-19 Research Platform

To be eligible to the competition, applications must address ALL objectives AND key design components:

• Establish central coordination and collaboration activities with Collaborating Sites located across Canada to increase the availability of high-quality and real-time evidence to support research on the effectiveness and relative safety of the COVID-19 vaccines in children and youth;
• Generate research evidence related to COVID-19 infection and vaccination consequences in diverse children and youth population(s), including (but not limited to):
  • Equity considerations;
  • Health and well-being status (e.g., historically excluded or underserved populations, individuals with complex health needs and/or a disability);
  • Sex and gender; and/or
  • Racialized and Indigenous (First Nations, Inuit, Métis and Urban Indigenous) populations.
• Identify children and youth populations at the highest and high risk for negative outcomes related to COVID-19 infection and/or vaccination consequences, and other determinant of health factors (e.g., social, economic, behaviour, etc.) that are associated with this increased greater risk.
• Harmonize data collection, and improve open and real-world data sharing with relevant knowledge-users in an accessible, useful and relevant format to support a timely and effective COVID-19 public health response within and across all jurisdictions in Canada as it relates to children and youth;
• Collaborate across Sites to establish resource and data sharing policies, increase efficiencies in research and related processes (including but not limited to ethics review; privacy considerations; contracts; informed-consent; common protocols; developing applications for trial funding; consistent and valid patient-oriented outcomes), reduce duplication, and maximize research and surveillance activities related to COVID-19 infection and/or vaccination consequences of children and youth; and
• Provide research evidence to inform clinical and health system management and public health response, and/or decision-making and planning within and all across jurisdictions in Canada and internationally.