Defense Health Program Department of Defense Lupus Research Program Anticipated Funding Opportunities for Fiscal Year 2021 (FY21)

How to Apply: 

he FY21 Defense Appropriations Act provides funding to the Department of Defense Lupus Research Program (LRP) to support the full spectrum of research projects or ideas that specifically focus on scientific and clinical lupus issues, which, if successfully addressed, have the potential to make a major impact in lupus research.  As directed by the Office of the Assistant Secretary of Defense for Health Affairs, the Defense Health Agency J9, Research and Development Directorate manages the Defense Health Program (DHP) Research, Development, Test, and Evaluation (RDT&E) appropriation.  The managing agent for the anticipated Program Announcements/Funding Opportunities is the Congressionally Directed Medical Research Programs (CDMRP) at the U.S. Army Medical Research and Development Command (USAMRDC).

 

The FY21 LRP Program Announcements and General Application Instructions for the following award mechanisms are posted on the Grants.gov website.    

 

Applications submitted to the FY21 LRP must address one or more of the following focus areas:

 

  • Understanding how lupus disease heterogeneity impacts risk of disease, disease presentation, clinical course, and outcomes; using a diverse range of research disciplines including, but not limited to, biopsychosocial studies, personalized medicine, variation in treatment studies, health economics, socioeconomic studies, environmental studies, and epidemiological studies.
  • Understanding mechanisms of lupus disease, using mechanistic studies, strategies, and technologies including, but not limited to, informative, rare patients.
  • Determining the pathobiology of end organ injury lupus disease in target human tissues.
  • Improving quality of life for individuals living with lupus including, but not limited to, addressing social determinants of health, access to healthcare resources, outcomes research, patient-reported outcomes, symptom and disease control, comparative effectiveness research, and issues and challenges that, when addressed, make day-to-day living with lupus easier and life more fulfilling.
  • Understanding the underlying genetic and epigenetic components and gene-environment interactions of lupus and how they may relate to clinical disease characteristics, variations, and differences in response to therapies using functional genomic studies.

 

Applications submitted to the FY21 LRP Transformative Vision Award must address the following Focus Area:

  • Design and implement an intervention including, at the individual and/or healthcare system level, improving quality of life for, but not limited to, access to healthcare resources, outcomes research, symptom and disease control, comparative effectiveness research, and issues and challenges that, when addressed, make day-to-day living with lupus easier and life more fulfilling.

 

https://cdmrp.army.mil/funding/lrp

 

Idea Award – Letter of Intent due August 24, 2021

Investigators at or above the level of postdoctoral fellow (or equivalent)

  • Supports innovative, high-risk/high-reward research that could ultimately lead to a critical discovery or major advancement relevant to lupus.
  • Must address one of the Fiscal Year 2021 (FY21) LRP Focus Areas.
  • Emphasis is on innovation
  • Clinical trials are not allowed
  • Preliminary data are not required.
  • The maximum allowable funding for the entire period of performance is $300,000 for total costs (direct plus indirect costs)
  • The maximum period of performance is 2 years

 

 

Impact Award – Letter of Intent due August 24, 2021

Independent investigators at or above Assistant Professor (or equivalent)

  • Supports high-risk/high-reward research which, if successfully addressed, has the potential to make a major impact in lupus research
  • Emphasis is on impact
  • Must address one of the FY21 LRP Focus Areas
  • Clinical trials are not allowed
  • Preliminary data are encouraged but not required
  • The maximum allowable funding for the entire period of performance is $750,000 for total costs (direct plus indirect costs)
  • The maximum period of performance is 4 years

 

Transformative Vision Award – Letter of Intent due August 24, 2021

Independent investigators at or above Assistant Professor (or equivalent)

  • Supports research that will have an intervention at the individual and/or healthcare system level, which will result in near-term impact on the health-related quality of life of persons living with lupus
  • Emphasis is on near-term impact to quality of life
  • Must address the FY21 LRP TVA Focus Area
  • Human subject research and clinical trials are allowed.
  • Preliminary data are required
  • Animal studies are not allowed.
  • Partnering Principal Investigators  (PI) Option allows one Initiating Investigator and a maximum of two Partnering PIs 
  • New – The research team must include one of more Consumer Advocate(s).
  • The maximum allowable funding for the entire period of performance is $2.5 million for total costs (direct plus indirect costs)
  • The maximum period of performance is 4 years

 

A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline.  All applications must conform to the final Program Announcements and General Application Instructions that will be available for electronic downloading from the Grants.gov website.  The application package containing the required forms for each award mechanism will also be found on Grants.gov.  A listing of all CDMRP and other USAMRDC extramural funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420. 

 

For email notification when Program Announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org.  For more information about the LRP or other CDMRP-administered programs, please visit the CDMRP website (https://cdmrp.army.mil).

 

Point of Contact:

CDMRP Help Desk
301-682-5507
help@eBrap.org

 

External Deadline: 
Tuesday, August 24, 2021
Funding Source: 
External
Funding Level: 
Research